- Home
- Assessments
- 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindenol[5,6-c]pyran - 1222-05-5
- Assessed: 2015-04-15
- Benchmark: Benchmark 1
- Send
Key Functions: Cosmetics & Personal Care
HHCB is a high production volume fragrance ingredient. It is one of the most common synthetic polycyclic musks, and is used in both consumer and commercial products. Technical grade Galaxolide consists of four diastereoisomers (i.e., isomers that differ in the spatial arrangement of atoms rather than being mirror images of each other), with HHCB as the major isomer. It is synthesized by alkylating I-methyl styrene and tertiary amylene with the catalyst sulfuric acid. The resulting pentamethyl indane is reacted with propylene oxide to form HHCB-alcohol. HHCB (undiluted) is formed by cyclization with paraformaldehyde. HHCB is then diluted to a pourable liquid. The name Galaxolide refers to HHCB diluted with diethyl phthalate.
Chemical Synonyms Galaxolide; Hexahydrohexamethyl cyclopentabenzopyran; 1,3,4,6,7,8-Hexahydro4,6,6,7,8,8-hexamethyl-cyclopenta-gamma-2-benzopyran; Hexahydro-4,6,6,7,8,8- hexamethylcyclopenta-gamma-2-benzopyran; Cyclopenta(g)-2-benzopyran, 1,3,4,6,7,8-hexahydro4,6,6,7,8,8-hexamethyl-; Galaxolide White; Abbalide; Pearlide, HHCB,